HORIZON Reference Standards
Gene Editing
Understand disease mechanisms at the genomic level
Edit-R gene editing reagents
Optimized tools for high-confidence genome engineering.
Cell models
Work with relevant cell models, specific to any application. Ready-to-go or tailored to individual needs.
Gene Modulation Reagents
Understand disease mechanisms at the genomic level
Gene knockdown
RNAi solutions by Dharmacon™ make gene silencing simple, so you can focus on the functional result!
Gene overexpression
CRISPR activation, cDNA & ORF reagents for reliable gene expression solutions to suit any workflow.
Top 3 tips for RNAi experiment success
Suggestions from our team of PhD trained scientists for getting your RNAi experiments working successfully!
Cell-based screening services
From target selection to patient stratification.
Working with you from consultation to delivery – providing functional genomic and cell panel screening services.
Functional genomic screens
Identify and characterize therapeutic targets and biomarkers
- Determine relevant gene function
- Investigate drug/gene interactions
- Ensure data quality – generated using the latest CRISPR or RNAi reagents
Cell panel screens
Identify cells that respond to your therapeutic
- Obtain trustworthy, reproducible data sets
- Receive full analysis and comprehensive report
- Screen in 2D and 3D models – spheroid and organoids
Screening libraries
Ensure library specificity – algorithm optimized guide RNA
- Choose from CRISPR, CRISPRa and RNAi, pooled and arrayed formats
- Freedom with custom library design
Immune cell-based assays
Evaluate therapeutic efficacy in immune-cell-based environments
Validation tools for molecular diagnostics
Consistency from assay development to routine monitoring
Next generation sequencing (NGS)
Bring consistency to NGS workflows
- From assay development to routine monitoring
- Mimic patient samples with commutable controls
Large panel NGS
Have confidence in large panel NGS worfklows
- OncoSpan – the largest oncology reference standard
- Multiple variant types, including structural and fusions
Sanger and qPCR
Reference standards at precise allele frequencies
- single gene, multi-variant controls
- well-characterized, commutable material